Objective(s): In developing countries and worldwide cervical cancer is an important cause of   female mortality. Reports describing the frequency and pattern of abnormal Pap smears in Saudi Arabia, using the revised Bethesda system (RBS) are very few. The current study was conducted to explore the changing pattern of epithelial cell abnormalities (ECA) detected in Pap smears (PS) in females of ...

conclusions this study describes robust information on the distribution of hpv genotypes among iranian women with and without cervical lesions. the present data may be of importance for designing future public health strategies, including hpv vaccination programs. results in total, hpv infection was detected in 45.4% of the cases. the most common high-risk hpv (hr-hpv) genotype was hpv-16 (32.8...

objective(s): in developing countries and worldwide cervical cancer is an important cause of   female mortality. reports describing the frequency and pattern of abnormal pap smears in saudi arabia, using the revised bethesda system (rbs) are very few. the current study was conducted to explore the changing pattern of epithelial cell abnormalities (eca) detected in pap smears (ps) in females of ...

The performance of endocervical curettage (ECC) is a dispute in population screening programs. Data of 3,460 women referred to colposcopy examination and had completed pathological results in the Shanxi Province Cervical Cancer Screening Study I and II were reviewed. Among them, 0.6% and 2.7% women were identified as the histopathological confirmed high-grade squamous intraepithelial lesion or ...

"Low-grade squamous intraepithelial lesion (LSIL), cannot exclude high-grade squamous intraepithelial lesion" (LSIL-H) is an increasingly used, equivocal interpretive category in gynecologic cytology. In an effort to evaluate its potential usefulness as a measure of quality assurance, we studied patterns of use of the LSIL-H diagnosis compared with "LSIL" and "high-grade squamous intraepithelia...

Results HPV-HR (high-risk) was positive in 377 cases, HPV-LR (low-risk) was positive in 165 cases and in 35 cases no HPV typing was performed. The herpes virus type 2 infection was present in 2 cases. Cytology showed LSIL (low grade squamous intraepithelial lesion) in 329 cases and HSIL (high grade squamous intraepithelial lesion) in 189 cases. Histological examination revealed cervical intraep...

CONTEXT Anal cytology is being used more frequently for anal cancer screening, yet many cytologists are unfamiliar with it. OBJECTIVE To describe the performance of anal cytology in the College of American Pathologists' Interlaboratory Comparison Program in Non-Gynecologic Cytology (CAP NGC) educational slide program during a 6-year time span, from 2006 to 2011, using participant responses (p...

We investigated the expression of Brother of Regulator of Imprinted Sites (BORIS) and CCCTC-binding factor (CTCF) in squamous intraepithelial lesions and cervical cancer. To analyze BORIS and CTCF expression, an endocervical cytobrush sample was taken for total RNA isolation. CTCF and BORIS mRNA was quantified from total RNA using quantitative reverse transcription-polymerase chain reaction. A ...

OBJECTIVE The aim of this research was to assess the immunofluorescence expression (IFE) of cell cycle regulators p16ink4a, p21, p27, in association with proliferation and prognosis factors Ki-67, p53 respectively, in cell cultures, obtained from different types of cervical intra-epithelial lesions. The final purpose was to distinguish a best marker able to identify with high accuracy the high-...